Glue and Pocket holes

I've got quite a few projects under my belt now, but I find myself asking a very basic question... I've got the Kreg Jig and I use pocket hole construction when I can. Up until now I have used glue on all the joints with pocket holes, because I it was my understanding that the glue is a major player in the structural soundness of the finished project, and that the pocket hole screws acted as clamps while the project dried (and also provide structural support as well, obviously). I watched one of Ana's videos, and I notice that she doesn't use glue when she assembled with pocket holes. I would love to give up glue when assembling with pocket holes!! Invariably I get some glue where I don't want it and darn it, the wood wants to slide around with glue on the joint--no way could I just put the boards together while holding it with one hand and screw the boards in place like she does on the video. Any advice? Can I ditch the glue with the pocket hole screws?